Are you looking for a way to jumpstart your weight loss journey? Are you tired of trying the same old fad diets with little success? If so, then this blog post is for you. We’re going to discuss the benefits of Mounjaro for weight loss. How Mounjaro can help you shed those extra pounds and keep them off.
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What is Mounjaro?
Mounjaro (tirzepatide) is the newest injectable medication for the treatment of type II diabetes and obesity. It is a once-weekly non-insulin injection for adults to help lower A1C levels, along with diet and exercise. Its active ingredient has been proven to be safe and effective in treating overweight or obesity, just as it does in adults with type-2 diabetes. Mounjaro was recently approved for the treatment of diabetes by the FDA in 2022 . It has also been shown to lead to significant weight loss when used alongside diet and exercise. In the Mounjaro® phase III weight loss trial published in the New England Journal of Medicine in June 2022, the average weight loss at 18 months on the medication was 20% or more of their body weight.
The Benefits of Mounjaro for Weight Loss
Mounjaro is a combination of two hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP). It mimics the action of these hormones and works to reduce appetite and slow down gastric emptying. This is how quickly food passes through your digestive system. Early data suggests that it may even be more effective than other diabetes medications in assisting with weight loss. Clinical trials have found that doses of tirzepatide are effective in reducing hemoglobin A1C levels, as well as helping with weight loss. In fact, Mounjaro showed the most significant weight loss compared to any other diabetes medication. The average weight loss after 52 weeks for Mounjaro was 28 pounds for those taking the highest dose of 15 milligrams. The 5-milligram dose of Mounjaro resulted in an average weight reduction of 4 pounds.
The Effects of Mounjaro on Type 2 Diabetes
Mounjaro is a prescription medication used to treat adults with type 2 diabetes. It is taken along with diet and exercise to help control blood sugar. The drug works by reducing the incretin effect, which can lead to hyperglycemia. Mounjaro also helps control other diabetes-related factors, such as A1C and cholesterol. In multiple studies, Mounjaro has been shown to reduce A1C levels and improve cholesterol markers in adults with type 2 diabetes. Additionally, it has been found to be more successful at treating type 2 diabetes when compared to other medications.
Mounjaro Safety and Side Effects
Mounjaro is generally considered safe and has relatively few side effects. In clinical studies of Mounjaro, the most common side effects included nausea, vomiting, diarrhea, upset stomach, constipation, loss of appetite, and injection site reactions. However, these side effects were mostly mild and tended to improve over time. As with all medications, it is important to talk to your doctor about any potential risks before taking Mounjaro.
Mounjaro Weight Loss Study Results
The SURMOUNT-1 trial looked closely at the effects of Mounjaro on weight loss. In this 40-week study, participants taking Mounjaro experienced significant weight loss, with the average participant losing 15% of their body weight over 72 weeks. Even at the lowest dose of 5 mg, participants still saw a reduction in body weight. The results of this study have been widely publicized and have shown that Mounjaro is a promising treatment option for those looking to lose weight.
Who Should Take Mounjaro?
Mounjaro is intended for adults with a body mass index greater than 30 or greater than 27 with an obesity-related medical condition (i.e. diabetes, high blood pressure). It is important to note that Mounjaro is not approved for weight loss alone and should be taken as part of a healthy lifestyle that includes exercise and a balanced diet. Patients should always consult their doctor before starting any new medication to make sure it is the right choice for them.
How to Take Mounjaro
Mounjaro is a prescription medication that is given as a weekly subcutaneous injection via a pre-filled syringe, which needs to be prescribed by your doctor. It comes in 6 different dose strengths, and you start Mounjaro at a dose of 2.5 mg once a week. Your doctor can increase the dose if needed, up to 15 mg per week. To get the most benefit from Mounjaro, it is important to take it as prescribed and take it with a balanced diet and regular exercise. Additionally, bi-weekly nutrition counseling with a Registered Dietitian may be recommended to ensure you get the most out of your Mounjaro treatment.
What Are the Alternatives to Mounjaro?
Mounjaro is not the only option available for those looking to lose weight. Other drugs, such as Saxenda, semaglutide (Wegovy), and Ozempic, have all been shown to help with weight loss. Saxenda is part of a treatment plan that includes diet and exercise, while semaglutide and Ozempic are approved by the FDA for chronic weight management. The effects of dulaglutide on weight loss vary depending on the dose and baseline BMI of the patient. Ultimately, it is important to discuss all options with your doctor to determine which medication is right for you. At Valley Forge Weight Management Center, Dr. Adarsh Gupta, who is a bariatrician (a physician with specialized training and certification in obesity management), will review your history and daily routine and develop a personalized plan to lose weight.
FDA Approval Status of Mounjaro for Weight Loss
The FDA has approved MounjaroTM (tirzepatide) to treat type 2 diabetes. Eli Lilly, the manufacturer, is expected to file for FDA approval for an indication of weight loss in the near future. Currently, the drug is not indicated for weight loss, despite promising results. In a phase 3 trial, patients on the highest (15-mg) dose of Mounjaro lost an average of 15 pounds more than placebo when neither was taking any other medication. Until the FDA approves Mounjaro as a weight loss medication, those seeking to lose weight should speak with their healthcare provider about other options, such as weekly injectable medications Ozempic and WeGovy.
- N Engl J Med 2022; 387:205-216. https://www.nejm.org/doi/full/10.1056/NEJMoa2206038